Why I Don't Recommend NSAID Drugs

 

pills.jpgWhy I Don't Recommend NSAID Drugs

NSAID's increase your risk of death from heart attack and stroke.  They increase serious risk of bleeding in the stomach and small intestine. And they are a significant cause of Leaky Gut Syndrome.  
Numerous studies show that they slow healing of connective tissue including fractures, surgical wounds and disc problems.  AND studies also show that many people get just as much relief from taking 2 grams of Omega 3 fatty acids.

 

The NSAID drugs, especially the Cox-2 inhibitors, like Vioxx, have been in the news because they increase deaths from heart disease.   In addition they have many other negative side effects.

Many studies confirm that NSAID drugs 1. Interfere with healing, especially of connective tissues such as bone, joint, ligament and muscle, 2.  Cause inflammation in the small intestine and may increase food intolerance. 3. Interfere with liver detoxification and 3. 

Here are some examples:

NSAID Drugs Slow Ligament Healing

A new study by Dr. Stuart J. Warden, from Indiana University in Indianapolis, and his colleagues, suggests that the use of NSAID drugs, such as Celebrex (celecoxib) and Motrin (ibuprofen), tends to slow the healing of knee ligaments after an injury.

They found that low-intensity pulsed ultrasound treatments can hasten the healing of torn knee ligaments. Before, it was standard practice to use NSAIDs and ultrasound together with knee injuries, and using them separately had not been studied.

“NSAIDs are fine if you just use them to control inflammation and pain for 3 or 4 days after injury,” Warden said. “But our findings suggest that you should get off of them as soon as you can because they can impair ligament healing.”

"In spite of the widespread use of NSAIDs there is no convincing evidence as to their effectiveness in the treatment of acute soft tissue injuries." (Bruckner, P. Clinical Sports Medicine. New York City, NY: McGraw-Hill Book Company, 1995, pp. 105-109.) 

NSAID's Prevent Proper Fracture Healing 

NSAID's: Why We Do Not Recommend Them  A review of the use of NSAIDS in sports injuries.

Indomethacin and Celecoxib Impair Rotator Cuff Tendon-to-Bone Healing   The American Journal of Sports Medicine 34:362-369 (2006)

Effects of Nonsteroidal Anti-Inflammatory Drugs on Bone Formation and Soft-Tissue Healing J Am Acad Orthop Surg, Vol 12, No 3, May/June 2004, 139-143.

Effects of NSAID's on Epithelial Tissue and Wound Healing   NSAID's also interfere with skin and wound healing.

NSAIDS cause small intestine inflammation and increase intestinal permeability which can lead to food allergies. Normally the intestinal lining is a barrier to food proteins.  NSAIDs cause swelling and inflammation which allows partially digested proteins to cross this barrier into the blood where the immune system sees them as foreign protein mounting an attack which we call food intolerance.  In some cases NSAIDs can cause serious bleeding in the small intestine which can be life threatening.  NSAID's cause an estimated 7,600 (or more) unnecessary deaths in the United States every year.

"Each year, use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) accounts for an estimated 7,600 deaths and 76,000 hospitalizations in the United States." (NSAIDs include aspirin, ibuprofen, naproxen, diclofenac, ketoprofen, and tiaprofenic acid.)

Source: Robyn Tamblyn, PhD; Laeora Berkson, MD, MHPE, FRCPC; W. Dale Jauphinee, MD, FRCPC; David Gayton, MD, PhD, FRCPC; Roland Grad, MD, MSc; Allen Huang, MD, FRCPC; Lisa Isaac, PhD; Peter McLeod, MD, FRCPC; and Linda Snell, MD, MHPE, FRCPC, "Unnecessary Prescribing of NSAIDs and the Management of NSAID-Related Gastropathy in Medical Practice," Annals of Internal Medicine (Washington, DC: American College of Physicians, 1997), September 15, 1997, 127:429-438, from the web at http://www.acponline.org/journals/annals/15sep97/nsaid.htm, last accessed Feb. 14, 2001, citing Fries, JF, "Assessing and understanding patient risk," Scandinavian Journal of Rheumatology Supplement, 1992;92:21-4.

NSAIDs interfere with liver function and at worst can cause severe liver damage. 
NSAIDs are toxic drugs whcih can be poisonous at higher levels.  The liver has to work harder to detoxify them.  One of the main ways the liver gets rid of NSAID's is by complexing with sulphur or sulphur amino acids such as cysteine, taurine or methionine.  So NSAID's use up these compounds which are needed to process other toxins and are also needed to heal joints and other connective tissue.

NSAID's cause an estimated 80% increase in risk of miscarriage.

People who have survived a first heart attack have a higher risk of dying or having a second heart attack if they are taking non-steroidal anti-inflammatory drugs (NSAIDs), including the newer class called cox-2 inhibitors.

There are natural alternatives:

 The key is matching the treatment to the patient.

 

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Inflammation and Cytokines

"Researchers are linking inflammation to an ever-wider array of chronic illnesses," reports Newsweek's Anne Underwood. "Suddenly medical puzzles seem to be fitting together, such as why hypertension puts patients at increased risk of Alzheimer's, or why rheumatoid-arthritis sufferers have higher rates of sudden cardiac death. They're all connected on some fundamental level."

 

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  Why You Need Alternative Healthcare  

We Don't Have a Health Care System, we have a disease care system and it's not working.  Americans spend more than any other country on health care and have the worst outcomes of any major industrialized country.   The medical system in not only an economic disaster but has been fundamentally corrupted by its financial ties to the drug and insurance industries. 


gmphoto.jpgDr. Manlove

  © 2011 George Manlove, DC   All rights reserved. 


Disclaimer: The entire contents of this website are based upon the opinions of Dr. Manlove, unless otherwise noted. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Manlove. Dr. Manlove encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.

 These statements have not been evaluated by the Food and Drug Administration. Products discussed in these articles are not intended to diagnose, treat, cure or prevent any disease.  If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any product.